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3 3 1 147 0 9 0 222 2 4 3 154 . 3 1 8 249 69 3 2 3 151 .. 1 4 1 240 70 1 3 4 141 .. 2 432 436 450 9 66 0 1 2 .. 4 4 149 127 134 62 1 1 7 3 7 7 1 4 2 3 7 7 4 2 5 6/10 2 3 1 3 6 2 2 8 0 1 2 5 119 385 121 8/10 5/8 4/6 9/9 5/8*' Table IV. M. M. Control 50 100 No. of Rats Start Finish 10 10 8 6 8 5 Total Food and Parathion Consumed, G . Control 50 100 132,955 103,284 % Mortality o f 40 20 38 Average Weight, G . /rat/day, Total, g. g. /rat/day, Total, g. g. , and the corresponding control group, were sacrificed b y exsanguination through a cardiac puncture following light ether anesthesia.

16) Stammers, F . M . , and Whitfield, F . G . , Bull. Entomol. Research, 38, 1-73 (1947). , Bayonne, N. , HOWARD A. JONES, U. S. , and LAWRENCE W. BASS, U. S. , New York, Ν. Y. ch011 In the search for safe insecticides, hundreds of products have been prepared and subjected to screening tests against insects. This paper presents information on six materials related to piperonyl butoxide, tested in combination with pyrethrins. W o r l d food shortages lend added weight to the importance of safe insecticides.

I n this respect i t is interesting to evaluate parathion according to a series of criteria postulated by Lehman (9) : Parathion is relatively toxic to insect life (Jf) as well as to mammals; therefore, under conditions of usage i t has a favorable ratio. Administration over a long period of time b y means of treated food produces no evidence of toxicity or accumulation i n doses which are acutely tolerated. Although a sex variation was observed i n rats, this is no greater following chronic exposure than following acute toxicity.

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